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Net water flow hyperosmotic side hypoosmotic side. Invertebrates are osmoregulators •marine bony fishes are hypoosmotic to sea water •they lose water by osmosis and gain salt by. Ions from gills gain of water and salt ions from food osmotic water loss through gills and other parts of body surface uptake of water and some ions in food. Control solute concentrations in the interstitial fluid and balance water gain and loss.